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ea0081ep892 | Reproductive and Developmental Endocrinology | ECE2022

Effects of letrozole on reproductive organs of young and aged male rats

Reznikov Alexander , Sachynska Olga , Polyakova Liubov , Faliush Oksana

The aim of this work was to study the condition of the reproductive system after long-term administration of letrozole followed by its withdrawal in young males and against the background of involutive changes in aging males in a comparative aspect. The experiments were carried out on Wistar rats with an initial age of 5 months and 15 months, which have been gavaged by letrozole every other day at a dose of 1 mg/kg body weight for 3 months and then 2 months after its discontin...